Herbal Remedy To Lower Blood Sugar in Diabetics Studied.
As people experience more and more adverse side effects from modern medications, the interest in alternative treatments such as herbal medicines have gained in popularity. Many herbal supplements have been used for thousands of years, prior to modern medicine, to great effect but were later discarded or discredited by the medical community. However, today we are seeing a resurgence in interest in herbal remedies as people are seeking to take better care of their bodies and avoid chemicals, sugars, fat and un-natural materials as much as possible. As a result many studies have arisen testing a variety of commonly used herbal treatments.
Many experiments have focused on the use of olive leaf in the treatment of diabetes and high blood sugar. Olive leaf has been used in the Middle East and Europe throughout the ages to lower blood sugar in diabetic patients and now these scientific studies are actually finding that oleuropein, a phenolic compound found in the olive leaf has a significant effect in eliminating some of the adverse effects of diabetes.
One such study published in 2005 (Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits, Al-Azzawie, et al., Life Sciences 78 (2006) 1371– 1377, July 11, 2005) showed that oleuropein, the active constituent of olive leaf, inhibited the hyperglycemia and oxidative stress of diabetes and suggested that supplementing with oleuropein may prevent diabetic complications resulting from oxidative stress.
The researchers conducted the study on 24 rabbits that were categorized into three groups; the first group were healthy rabbits were used as a control group, the second group were diabetic rabbits that received no supplements and were also a control group, and the third group were diabetic rabbits that received a daily oral dose of 20 mg/kg of olive leaf extract for 16 weeks.
The diabetic groups of rabbits were treated with alloxan intravenously and those who exhibited significant increase in blood glucose above 200 mg/dl were used in the study as diabetic subjects.
The researchers found that the oleuropein-treated rabbits levels of blood glucose were significantly lower in rabbits treated with oleuropein as compared with the untreated diabetic rabbits who continued to exhibit high glucose levels throughout the study period.
After 20 days of induction of diabetes, the diabetic rabbits that had not been supplementing with oleuropein had a significant increase in oxidative stress as determined by the oxidative stress marker MDA. The diabetic rabbits supplemented with oleuropein experienced a gradual decline in MDA upon beginning herbal treatment compared with the un-supplemented diabetic control group culminating in a significant difference by week 10 as compared with diabetic rabbits that did not receive herbal supplements. In comparison, the diabetic rabbits that were not given herbal supplements had their MDA constantly and significantly elevated as compared with the control group of healthy rabbits.
The researchers concluded, “this study demonstrated the beneficial effect of using oleuropein as an effective hypoglycemic and antioxidant agent in alleviating oxidative stress and free radicals as well as in enhancing both enzymatic and nonenzymatic defenses diabetes” and “this study demonstrated another potential and beneficial effect of oleuropein in attenuating oxidative stress and enhancing of body’s own antioxidant defenses in diabetic rabbits with established oxidative stress and may add another explanation of the hypoglycemic effect of oleuropein through its action as an antioxidant.”
You can read the entire published study here Herbal Remedy To Lower Blood Sugar in Diabetics Studied.
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